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[相差显微镜在成人血尿病因诊断中的价值。第一部分。确立肾小球性血尿的个体标准]

[Values of phase-contrast microscopy in the etiological diagnosis of hematuria in adults. Part I. Establishing individual norms for glomerular hematuria].

作者信息

Obroniecka I

机构信息

Kliniki Nefrologii ze Stacja Dializ, Centralnego Szpitala Klinicznego WAM.

出版信息

Pol Merkur Lekarski. 1998 Nov;5(29):277-9.

Abstract

UNLABELLED

In the cohort of 123 patients (average age 44 years) criteria for glomerular and nonglomerular hematuria (H) were established by phase-contrast microscopy (PCM). According to literature, hematuria was divided into glomerular, mixed or nonglomerular if: > 60%, 20-60% and < 20% dysmorphic erythrocytes (E) of fresh morning urine sediment were found. Diagnosis of glomerulonephritis was confirmed by renal biopsy in 54/57 glomerular H as well as in all 8 cases of mixed H. On the contrary, urological reasons for H were found in 55/58 cases of nonglomerular H with normal renal biopsy in the remaining 3 patients. Using value > 20% of dysmorphic E as a new norm for glomerular H, we found sensitivity and specificity of this test as 100% and 95% respectively.

IN CONCLUSION

glomerular H should be suspected and renal biopsy recommended when > 20% dysmorphic E are found by PCM what means exclusion of the term "mixed H".

摘要

未标注

在123例患者队列(平均年龄44岁)中,通过相差显微镜检查(PCM)确定肾小球性和非肾小球性血尿(H)的标准。根据文献,如果清晨新鲜尿沉渣中畸形红细胞(E)分别>60%、20 - 60%和<20%,则血尿分为肾小球性、混合性或非肾小球性。54/57例肾小球性H以及所有8例混合性H通过肾活检确诊为肾小球肾炎。相反,55/58例非肾小球性H中发现泌尿系统原因导致血尿,其余3例肾活检正常。以畸形E>20%作为肾小球性H的新标准,我们发现该检测的敏感性和特异性分别为100%和95%。

结论

当通过PCM发现畸形E>20%时应怀疑肾小球性H并建议进行肾活检,这意味着排除“混合性H”这一术语。

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