Khoo B P, Ng S K
National Skin Centre, Singapore.
Ann Acad Med Singap. 1998 Nov;27(6):868-72.
Cutaneous polyarteritis nodosa (CPN) is an uncommon form of vasculitis. It exists as a separate entity, though bearing similar name with polyarteritis nodosa (PAN) which is an aggressive systemic vasculitis with multi-organ involvement. CPN runs a chronic but benign course. Its aetiology is unknown and it usually presents with painful nodules on the legs with mild constitutional symptoms, and extracutaneous features of arthralgias, arthritis, neuropathy and myopathy. No mortality has been reported thus far. It is therefore important to distinguish CPN apart from PAN. Symptomatic treatment with judicial use of systemic steroids and anti-inflammatory agents will suffice in most cases.
皮肤型结节性多动脉炎（CPN）是一种罕见的血管炎形式。它作为一个独立的实体存在，尽管与结节性多动脉炎（PAN）名称相似，而PAN是一种侵袭性的系统性血管炎，可累及多个器官。CPN病程呈慢性但良性。其病因不明，通常表现为腿部出现疼痛性结节，并伴有轻度全身症状，以及关节痛、关节炎、神经病变和肌病等皮肤外表现。迄今为止尚未有死亡病例报道。因此，将CPN与PAN区分开来很重要。在大多数情况下，合理使用全身性类固醇和抗炎药进行对症治疗就足够了。
