Kleeman D, Kempf W, Burg G, Hafner J
Department of Internal Medicine, City Hospital Triemli, Zurich, Switzerland.
Vasa. 1998 Feb;27(1):54-7.
Here we present two characteristic cases of cutaneous polyarteritis nodosa (cutaneous PAN). Cutaneous PAN is characterized by a chronic relapsing benign course over many years. In its mild form it presents with live-do and multiple painful nodular skin lesions mainly of the legs. In its more severe form painful skin ulcerations occur that are often accompanied by discrete polyneuropathy. Progression to systemic PAN is the exception. Only the more severe kinds of cutaneous PAN require a low-dose immuno-suppression. Assessment and treatment of cutaneous PAN are discussed.
在此,我们展示两例皮肤型结节性多动脉炎(皮肤型PAN)的典型病例。皮肤型PAN的特征是多年来呈慢性复发性良性病程。其轻症形式表现为网状青斑以及主要出现在腿部的多个疼痛性结节性皮肤病变。在其更严重的形式中,会出现疼痛性皮肤溃疡,常伴有单发的多发性神经病。进展为系统性PAN的情况较为罕见。只有更严重类型的皮肤型PAN需要低剂量免疫抑制治疗。本文讨论了皮肤型PAN的评估与治疗。