Steele N C, Frobish L T
Growth. 1976 Dec;40(4):369-78.
The effects of genetic phenotype (lean or obese), age, feeding frequency (ad-libitum or meal-fed) and dietary energy source (starch or lard) on selected enzymatic indices of lipogenesis in swine adipose tissue were investigated. The obese line maintained greater specific activities for citrate cleavage enzyme, glucose-6-phosphate dehydrogenase, 6 phosphogluconate dehydrogenase and malic enzyme compared to the lean line regardless of dietary factors. Dietary lard depressed lipogenic enzyme activity, except that of 6-phosphogluconate dehydrogenase, of adipose tissue homogenates in a similar manner in both genetic phenotypes. The enzymatic indices did not indicate that meal-feeding induced hyperlipogenesis can be produced in swine. The genetic phenotype of swine is the preponderant factor regulating lipogenic enzyme activities compared to dietary manipulations.
研究了遗传表型（瘦肉型或肥胖型）、年龄、饲喂频率（自由采食或定时定量饲喂）和日粮能量来源（淀粉或猪油）对猪脂肪组织中选定的脂肪生成酶指标的影响。无论日粮因素如何，肥胖品系的柠檬酸裂解酶、葡萄糖-6-磷酸脱氢酶、6-磷酸葡萄糖酸脱氢酶和苹果酸酶的比活性均高于瘦肉型品系。日粮中的猪油以类似方式降低了两种遗传表型脂肪组织匀浆中脂肪生成酶的活性，但6-磷酸葡萄糖酸脱氢酶除外。酶指标并未表明定时定量饲喂能诱导猪产生高脂生成。与日粮处理相比，猪的遗传表型是调节脂肪生成酶活性的主要因素。
