Ovulen-50（双醋炔诺醇1毫克和炔雌醇0.05毫克）对大鼠肝脏中蛋白质、核酸和核酸酶的影响。
Effect of Ovulen-50(ethynodiol diacetate 1 mg and ethynyloestradiol 0,05 mg) on protein, nucleic acids and nucleases in the rat liver.
作者信息
Mukundan M A, Bamji M S
出版信息
Int J Vitam Nutr Res. 1976;46(4):492-5.
PMID:1010688
Abstract
Treatment of adult female rats with Ovulen-50 (ethynodiol diacetate 1.0 mg and ethynyloestradiol 0.05 mg--one tenth tablet per day) led to a small but significant fall in total protein, RNA and DNA content of the liver. Alkaline and acid DNAse activity also tended to decline, whereas alkaline RNAase tended to show a marginal rise after twentyfour days of treatment.
摘要
用Ovulen - 50（双醋炔诺醇1.0毫克和炔雌醇0.05毫克——每天十分之一片）对成年雌性大鼠进行治疗，导致肝脏总蛋白、RNA和DNA含量出现小幅但显著的下降。碱性和酸性DNA酶活性也有下降趋势，而碱性RNA酶在治疗24天后有轻微上升趋势。
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