两名苯丙酮尿症（PKU）儿童与两名正常儿童服用阿斯巴甜负荷剂量的结果比较。
Results of loading doses of aspartame by two phenylketonuric (PKU) children compared with two normal children.
作者信息
Koch R, Schaeffler G, Shaw N F
出版信息
J Toxicol Environ Health. 1976 Nov;2(2):459-69. doi: 10.1080/15287397609529447.
PMID:1011297
Abstract
Separate tolerance tests with aspartame at 34 mg/kg-day and phenylalanine at 19 mg/kg-day were compared. The results reveal that slight serum elevation of phenylalanine and tyrosine occurred in the two PKU and the normal healthy adolescents. It would appear that the phenylalanine in the sweetener aspartame is small enough to be of little clinical significance.
摘要
对分别以34毫克/千克·天的阿斯巴甜和19毫克/千克·天的苯丙氨酸进行的耐受性测试进行了比较。结果显示，两名苯丙酮尿症患者和正常健康青少年的血清苯丙氨酸和酪氨酸略有升高。看来甜味剂阿斯巴甜中的苯丙氨酸含量足够少，临床意义不大。
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