大鼠吸入二氯四氟乙烷（Arcton 114，C2Cl2F4）后的心电图变化

Electrocardiographic changes in rats after inhalation of dichlorotetrafluoroethane, Arcton 114, C2Cl2F4.

作者信息

Durakovic Z, Stilinovic L, Bakran I

出版信息

Jpn Heart J. 1976 Nov;17(6):753-9. doi: 10.1536/ihj.17.753.

DOI:10.1536/ihj.17.753

Abstract

The effects of dichlorotetrafluoroethane, Arcton 114, on the heart of rats were examined in 17 white rats. The animals inhaled dichlorotetrafluoroethane for 1 or 1.5 min. Severe electrocardiographic changes including marked bardycardia, atrioventricular heart block of the second degree and complete heart block were registered. Cardiac standstill appearing 11 to 31 min after inhalation was a death cause in all rats. These results are similar to our previous results concerning the effects of dichlorodifluoromethane (Arcton 12) on the heart of rats.

摘要

在17只白鼠身上研究了二氯四氟乙烷（商品名：Arcton 114）对大鼠心脏的影响。这些动物吸入二氯四氟乙烷1或1.5分钟。记录到严重的心电图变化，包括显著的心动过缓、二度房室传导阻滞和完全性心脏传导阻滞。吸入后11至31分钟出现的心搏停止是所有大鼠的死亡原因。这些结果与我们之前关于二氯二氟甲烷（商品名：Arcton 12）对大鼠心脏影响的结果相似。