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[衰老对心肌中RNA和蛋白质合成与分解的影响]

[Influence of aging on synthesis and breakdown of RNA and protein in the myocardium].

作者信息

Iavich M P

出版信息

Kardiologiia. 1976 Nov;16(11):56-60.

PMID:1011468
Abstract

The rate of decomposition of RNA and proteins in the heart muscle of aged rats, as well as the effect of t-RNA on the rate of translation in the reconstructed non-cellular system of protein synthesis were studied. The rate of decomposition of sarcoplasmatic and myofibrill proteins and RNA is known to be decreased in the heart muscle of old animals. The metabolic changes. The addition of homologous t-RNA to the non-cellular system of protein synthesis was shown to stimulate the incorporation of labelled amino acids into the ribosomes of the heart of old rats.

摘要

研究了老年大鼠心肌中RNA和蛋白质的分解速率,以及t-RNA对蛋白质合成重构无细胞系统中翻译速率的影响。已知老年动物心肌中肌浆蛋白、肌原纤维蛋白和RNA的分解速率会降低。代谢变化。向蛋白质合成无细胞系统中添加同源t-RNA可刺激标记氨基酸掺入老年大鼠心脏的核糖体中。

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