Spesivtseva V G, Lepeshkov V M, Frenkel' V Kh, Chernyshova N E
Kardiologiia. 1976 Aug;16(8):103-6.
Glomerular filtration was examined by way of a radioisotope technique using Yb169-labelled ethylenediaminetetracetic acid. The method permits to conduct the examinations without radio-isotope equipment at the bedside of myocardial infarction patients, which is of great practical convenience. The study was conducted in 65 myocardial infarction patients and in 14 control individuals. Glomerular filtration was studied dynamically in different age-groups, in patients with acute and recurrent myocardial infarction with due regard of concomitant hypertension and complications. A correlation of the disorders in glomerular filtration and the age of the patients was revealed. The lowest figures of glomerular filtration were received in patients with myocardial infarction complicated by circulatory insufficiency and, especially, cardiogenic shock. The indices of glomerular filtration correlated with the circulating blood volume and venous pressure not in all patients.
采用放射性同位素技术，以169Yb标记的乙二胺四乙酸来检测肾小球滤过功能。该方法可在心肌梗死患者床边无需放射性同位素设备的情况下进行检测，具有极大的实际便利性。本研究纳入了65例心肌梗死患者和14名对照个体。对不同年龄组、急性和复发性心肌梗死患者，以及伴有高血压和并发症的患者的肾小球滤过功能进行了动态研究。揭示了肾小球滤过功能障碍与患者年龄之间的相关性。肾小球滤过率最低值出现在合并循环功能不全，尤其是心源性休克的心肌梗死患者中。并非所有患者的肾小球滤过指标都与循环血容量和静脉压相关。
