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["洋地黄类药物所致心律失常及其治疗"]

["Digitalis" arrhythmias and their treatment].

作者信息

Doshchitsin V L

出版信息

Kardiologiia. 1976 Aug;16(8):26-31.

PMID:1011501
Abstract

The observation was conducted in 92 patients with rhythm and conductivity disorders induced by cardiac glycosides. Most of the patients had ischaemic heart disease, 60 of them having had acute myocardial infarction. All patients were prescribed cardiac glycosides (usually Strophantin and digitalis preparations) due to the appearance of cardiac insufficiency. The most frequently observed rhythm disorder consisted in ventricular extrasystole (69.5% of the cases), bigeminy, polytopic or group extrasystole being observed in many cases. Often arrhythmias consisted in atrial extrasystole, atrial fibrillation, atrial and ventricular tachycardia, atrioventricular block. "Digitalis" arrhythmias were treated with beta-adrenergic blockers: Inderal, Viskene, Eraldin, Trasicor and Aptin. These drugs proved effective in most cases with atrial arrhythmias and in some--with ventricular arrhythmias. Lidocain was more effective in cases of ventricular arrhythmias. Effective drugs of a broad spectrum are also Aimalin, Pulsenorma and Ritmodan.

摘要

对92例由强心苷引起的节律和传导障碍患者进行了观察。大多数患者患有缺血性心脏病,其中60例曾发生急性心肌梗死。由于出现心功能不全,所有患者均被给予强心苷(通常为毒毛花苷和洋地黄制剂)。最常观察到的节律紊乱为室性期前收缩(69.5%的病例),许多病例中还观察到二联律、多源性或成组期前收缩。心律失常常包括房性期前收缩、心房颤动、房性和室性心动过速、房室传导阻滞。“洋地黄”心律失常用β - 肾上腺素能阻滞剂治疗:心得安、烯丙心安、心得宁、心得舒和阿普林定。这些药物在大多数房性心律失常病例中被证明有效,在一些室性心律失常病例中也有效。利多卡因对室性心律失常病例更有效。广谱有效药物还有乙胺碘呋酮、脉律定和利搏律定。

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