Miller M, Barranda E G, Dean M C, Brush F R
Pharmacol Biochem Behav. 1976;5(Suppl 1):35-40. doi: 10.1016/0091-3057(76)90326-9.
Avoidance learning and extinction of rats with hereditary hypothalamic diabetes insipidus (Brattleboro strain) were studied in 2 experiments that differed only in shock intensity. In both experiments rats homozygous for diabetes insipidus were more deficient in both escape and avoidance responding than were their heterozygous or normal controls. Although the hterozygous animals showed improved escape performance at the higher shock intensity, their avoidance behavior was not improved. The superiority of normal and heterozygous animals in extinction performance, relative to the homozygous animals, was eliminated or reversed when the differences in terminal acquisition performance were taken into account by analyses of covariance. Deficiency of ADH, therefore, may not result in faster extinction of avoidance behavior.
在两项仅电击强度不同的实验中，对遗传性下丘脑性尿崩症大鼠（布拉特洛伯品系）的回避学习和消退进行了研究。在这两项实验中，尿崩症纯合子大鼠在逃避和回避反应方面比其杂合子或正常对照大鼠更差。尽管杂合子动物在较高电击强度下逃避表现有所改善，但其回避行为并未改善。当通过协方差分析考虑最终习得表现的差异时，正常和杂合子动物在消退表现方面相对于纯合子动物的优势被消除或逆转。因此，抗利尿激素缺乏可能不会导致回避行为更快消退。
