Szymusiak-Mutnick B, Mutnick A H
University of Iowa Hospitals and Clinics, Iowa City 52242.
J Pharm Technol. 1994 Jan-Feb;10(1):23-6. doi: 10.1177/875512259401000106.
To introduce the reader to the fundamentals involved in using decision analysis as a tool in evaluating the associated costs and effectiveness of comparable therapeutic agents.
Currently available literature citations were used to provide the reader with basic references whose purpose is to provide a step-by-step approach for using Decision Analysis in conducting a cost-effective comparison of three commonly used antibiotics. Data were gathered from a previously conducted retrospective chart review where the three antibiotics were used for either prophylactic, empiric, or documented infections. Although this study was limited by its retrospective nature, the reader can use the data to appreciate the fundamentals of decision analysis.
The continually changing climate in healthcare and the added visibility of pharmacologic agents in the treatment and prevention of disease has increased pressure on pharmacy departments to provide therapeutic agents that are cost-effective. Decision analysis can be used to compare therapeutic agents, in terms of financial as well as clinical outcomes, in a structured fashion that all members of the health care team can understand. The application of Decision analysis is appropriate for many therapeutic agents, not just antibiotics.
向读者介绍将决策分析作为一种工具用于评估可比治疗药物的相关成本和有效性所涉及的基本原理。
使用当前可得的文献引用为读者提供基本参考文献，其目的是提供一种逐步方法，用于在对三种常用抗生素进行成本效益比较时使用决策分析。数据收集自先前进行的回顾性病历审查，其中这三种抗生素用于预防性、经验性或已记录的感染。尽管该研究受其回顾性性质的限制，但读者可利用这些数据来理解决策分析的基本原理。
医疗保健领域不断变化的形势以及药物在疾病治疗和预防中的更高关注度，给药房部门带来了更大压力，要求其提供具有成本效益的治疗药物。决策分析可用于以一种医疗团队所有成员都能理解的结构化方式，在财务和临床结果方面比较治疗药物。决策分析的应用适用于许多治疗药物，而不仅仅是抗生素。
