Okpara A U, Van Duyn O M, Cate T R, Cheung L K, Galley M A
Ben Taub General Hospital, TX.
Hosp Formul. 1994 May;29(5):392-4, 399, 402-4.
Ceftazidime use at our institution, a 580-bed county teaching hospital, has steadily increased since its addition to the formulary in 1986. In response to this increased use and because the institutional antibiogram showed increased resistance by Pseudomonas aeruginosa (from 10 to 28% resistant), the P & T Committee requested that a drug use evaluation (DUE) of ceftazidime be conducted. Analysis of this retrospective pilot study showed that 87% of ceftazidime use was inappropriate. To further evaluate ceftazidime use, to identify problems not assessed during retrospective review, and to correct problems while patients were receiving the drug, a concurrent ceftazidime use evaluation was conducted. The methods and results of the concurrent review are presented below.
在我们这家拥有580张床位的县级教学医院，自1986年头孢他啶被列入药品处方集以来，其使用量一直在稳步增加。鉴于使用量的增加，且机构抗菌谱显示铜绿假单胞菌的耐药性有所上升（耐药率从10%升至28%），药品与治疗学委员会要求对头孢他啶进行药物使用评估（DUE）。对这项回顾性试点研究的分析表明，87%的头孢他啶使用是不恰当的。为了进一步评估头孢他啶的使用情况，识别回顾性审查期间未评估的问题，并在患者用药期间纠正问题，开展了一项头孢他啶同步使用评估。以下介绍同步审查的方法和结果。
