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当前的临床变革。基因疗法在疾病治疗中的应用。

The current clinical revolution. Applications of gene therapy in treatment of disease.

作者信息

Worden M

机构信息

Chiron Corporation, Emeryville, CA.

出版信息

Physician Assist. 1994 May;18(5):83-8.

Abstract

A major technological revolution is on the horizon that promises cures for inherited diseases such as cystic fibrosis, sickle cell anemia, muscular dystrophy, hemophilia, leukocyte-adhesion deficiency, and Gaucher's disease. This revolutionary technology also promises effective treatments for acquired diseases such as cancer and AIDS. The technique is gene therapy and it has already been used in humans. Some applications raise ethical considerations that not only affect the individual who is treated but have implications for future generations as well.

摘要

一场重大的技术革命即将来临,有望治愈诸如囊性纤维化、镰状细胞贫血、肌肉萎缩症、血友病、白细胞黏附缺陷症和戈谢病等遗传性疾病。这项革命性技术还有望有效治疗诸如癌症和艾滋病等后天性疾病。这项技术就是基因疗法,而且它已经在人体上得到应用。一些应用引发了伦理方面的考量,这些考量不仅影响接受治疗的个体,对后代也有影响。

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