Ketz E, Holdener E
Schweiz Med Wochenschr. 1976 Dec 18;106(51):1862-6.
In the light of 3 personally observed cases a description is given of polyradiculitis cranialis or socalled Fisher's syndrome, a separate form of Guillain-Barre-Strohl polyradiculitis. It is a combination of acute ataxia, areflexia and ophthalmoplegia. The cause is probably an immunological reaction to a harmless infectious disease. Reversible or limited demyelination is assumed. The demyelination occurs particularly in the peripheral nerves and their spinal roots, but also in the spinal-cerebellar pathways and possibly in the nuclei of the cranial or optic nerves. Diagnosis is based on detection of "albumino-cytologic dissociation" in the cerebrospinal fluid and the finding of a lesion of the peripheral motor neuron in the EMG. Special drug therapy is unnecessary. The prognosis is good: complete remission is usually observed.
根据3例亲自观察到的病例,对颅多神经根炎或所谓的费希尔综合征进行了描述,它是格林-巴利-施特罗尔多神经根炎的一种独立形式。它是急性共济失调、反射消失和眼肌麻痹的组合。病因可能是对无害传染病的免疫反应。推测存在可逆或局限性脱髓鞘。脱髓鞘尤其发生在周围神经及其脊神经根,但也发生在脊髓小脑通路,可能还发生在颅神经或视神经核。诊断基于脑脊液中“蛋白细胞分离”的检测以及肌电图中周围运动神经元病变的发现。无需特殊药物治疗。预后良好:通常可观察到完全缓解。