[Indications for amniocentesis for prenatal determination of fetal karyotype].

Analysis of the data from 13 centres of prenatal diagnosis in different countries revealed that 35 out of 1532 pregnancies where diagnostical amniocentesis was performed terminated in "spontaneous" abortions. The frequency of "spontaneous" abortions was found to be 2.28%. It was supposed that only those situations where a risk of the chromosomal disbalance in the fetus is above 2% may be regarded as the indications to amniocentesis for karyotype prenatal determination.