油附卡介苗细胞壁骨架及胸腺切除对兔化学致癌剂诱发肺癌和淀粉样变发生率的影响。
Effect of oil-attached BCG cell-wall skeleton and thymectomy on the incidence of lung cancer and amyloidosis induced by chemical carcinogens in rabbits.
作者信息
Hirao F, Nishikawa H, Yasaki S, Ogura T, Azuma I, Taniyama T, Yoshimoto T, Kishimoto S, Yamamura Y
出版信息
Gan. 1978 Aug;69(4):453-9.
Intravenous injection of oil-attached BCG cell-wall skeleton showed potent preventive activity for induction of lung cancer by the intrabronchial instillation of chemical carcinogens (3-methylcholanthrene, 4-nitroquinoline 1-oxide) in rabbits. On the other hand, the thymectomized rabbits developed lung cancer by instillation of chemical carcinogens at an 80% incidence, compared to 47.2% in the controls. There were no differences in the appearance of amyloidosis between thymectomized and BCG cell-wall skeleton-treated rabbits and the controls.
静脉注射附着油的卡介苗细胞壁骨架，对通过向兔支气管内滴注化学致癌物（3-甲基胆蒽、4-硝基喹啉 1-氧化物）诱导肺癌具有强大的预防活性。另一方面，胸腺切除的兔通过滴注化学致癌物发生肺癌的发生率为80%，而对照组为47.2%。胸腺切除的兔、卡介苗细胞壁骨架处理的兔与对照组之间，淀粉样变性的出现没有差异。
Zotero 插件