Komarova L V, Trapeznikov A A, Volkova N G
Ukr Biokhim Zh. 1976;48(6):690-4.
It is found out that surface pressure of catalase monolayers increases when some medicinal surface-active agents are added to its substrate, while its enzymic activity decreases depending on the increase of surface activity of the medicinal substance. Catalase monolayer viscosity grows with a decrease in the area. The viscosity decreases with a rise in the dimedrol concentration in the substrate. The same is recorded for the shear module. As to the shear stress characterizing the strength of the monolayers it decreases with the addition of medicinal substances. This change in rheological properties of the catalase monolayer evidences for its structural destruction with an increase in the mixed monolayer pressure.
研究发现,当向过氧化氢酶单层的底物中添加某些药用表面活性剂时,其表面压力会增加,而其酶活性会随着药用物质表面活性的增加而降低。过氧化氢酶单层的粘度随着面积的减小而增大。粘度随着底物中苯海拉明浓度的升高而降低。剪切模量也有同样的情况。至于表征单层强度的剪切应力,它会随着药用物质的添加而降低。过氧化氢酶单层流变学性质的这种变化表明,随着混合单层压力的增加,其结构遭到破坏。