Radushkevich V P, Radushkevich I V, Machnev L P
Vestn Khir Im I I Grek. 1976 Dec;117(12):81-4.
The results of treatment in 28 patients with extremely severe multiple injuries are analysed: 21 of them had open, comminuted, crushed fractures or tearing of 44 extremities. After a failure of antishock measures an assist extracorporeal circulation with oxygenation was instituted, and surgery was performed. In 128 experiments on dogs a explosive bullet wound was inflicted on the knee joint: a comminuted intraarticular fracture of 2-3 bones was produced, followed by 25-30% bloodletting and additional trauma of the damage site. In 23 control experiments without using the heart-lung machine but with routine antishock measures 83% of animals died after the amputation and 17%--survived. A conclusion is made on the rationale and efficacy of an assist extracorporeal circulation in severe traumatic shock, that would make is possible to perform an early operation and to eliminate "the trigger mechanism" of shock.
分析了28例极重度多发伤患者的治疗结果：其中21例有开放性、粉碎性、挤压性骨折或44处肢体撕裂伤。抗休克措施失败后，实施了带氧合的辅助体外循环，并进行了手术。在128只狗身上进行实验，造成膝关节爆炸性枪伤：导致2 - 3块骨头的关节内粉碎性骨折，随后放血25 - 30%并对损伤部位进行额外创伤。在23例未使用心肺机但采取常规抗休克措施的对照实验中，83%的动物截肢后死亡，17%存活。得出了辅助体外循环在严重创伤性休克中的理论依据和疗效的结论，这将使早期手术成为可能并消除休克的“触发机制”。
