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[鱼类体内3,4-苯并芘的组织蓄积及消除可能性]

[Possibility of tissue accumulation and elimination of 3,4-benzpyrene from the bodies of fish].

作者信息

Baranova L N, Dikun P P, Ostroumova I N, Timoshina L A

出版信息

Vopr Onkol. 1976;22(11):102-5.

PMID:1014502
Abstract

One-year and two-year iridescent trout and two-year carp during different periods (from 2 months to 1 year) were given protein-vitamin addition to food containing 3,4-benz-pyrene (BP). The total amount of BP entering the organism of fish for the whole period of the experiment reached 12,6 mg/Kg of fish weight in daily dosage ranging from 0.1 to 4.1 m/Kg. In fish tissues BP was either not detected at all, or the content of the carcinogen in them did not exceed its amount in the control. In summer BP was not excreted in feces, but in winter its excretion made 13% of its daily consumption with food.

摘要

在不同时期(从2个月到1年),给1岁和2岁的虹鳟鱼以及2岁的鲤鱼投喂添加了蛋白质维生素的含3,4-苯并芘(BP)的食物。在整个实验期间,进入鱼体内的BP总量达到12.6毫克/千克鱼体重,日剂量范围为0.1至4.1毫克/千克。在鱼组织中,要么根本检测不到BP,要么其中致癌物的含量不超过对照组中的含量。夏季时,BP不会通过粪便排出,但在冬季,其排泄量占每日食物摄入量的13%。

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