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采用高蛋白、高脂肪、“无碳水化合物”饮食治疗肥胖症

[Treatment of obesity with a high-protein, high-fat, "carbohydrate-free" diet].

作者信息

Tashev T, Goranov I, Ekimova S, Shishkov G, Dzhamba Ia

出版信息

Vutr Boles. 1976;15(5):50-6.

PMID:1014611
Abstract

Sanatorium treatment for 27 days was carried out for 52 patients with obesity of alimentary metabolism type, consisting of moderate loading and high-protein, high-lipid diet with 2430 to 2840 cal daily, with unusually low carbohydrate contents--10 g for the first week and 38 g--in the fourth. The authors established a favourable total and an average daily body weight loss of the patients, irrespectively of the relatively high caloric intake. No sense of hunger was reported from the majority of the patients. The subjective complaints observed are more frequent and more severe, as compared with the other treatment regimens with reducing but balanced dietetic regimens. The majority of the subjective complaints established could be associated with the objectively confirmed compensated metabolic ketoacidosis. The unfavourable changes in the followed-up laboratory indices are: considerable decrease of blood sugar, massive ketonuria, elevation of serum uric acid and deviations in the acid-base parameters. Serum lipid indices fell under the effect of the treatment and body weight reduction. What impresses is the serum cholesterol reduction in spite of the high exogenic import, the diminution of cholesterol-lecithin index and the marked elevation of free fatty acid in serum, manifestation of incresed lipolysis in the lipid depots. (he diet indicated is not balanced and not physiological. It must be applied casually in obesity treatment. Its application is possible only after a strict assessment of each individual patient with obesity with no accompanying diseases, that do not agree with the partial fasting and cannot be included in intensive motor regimen.

摘要

对52例 alimentary 代谢型肥胖患者进行了为期27天的疗养院治疗,治疗包括适度负荷以及高蛋白、高脂肪饮食,每日热量为2430至2840卡路里,碳水化合物含量异常低——第一周为10克,第四周为38克。作者发现,尽管热量摄入相对较高,但患者总体体重和日均体重均出现了有利下降。大多数患者未报告有饥饿感。与其他采用低热量但营养均衡饮食方案的治疗方法相比,观察到的主观不适症状更为频繁和严重。所确定的大多数主观不适症状可能与客观证实的代偿性代谢性酮症酸中毒有关。随访实验室指标的不利变化包括:血糖大幅下降、大量酮尿、血清尿酸升高以及酸碱参数异常。治疗和体重减轻使血清脂质指标下降。令人印象深刻的是,尽管外源性摄入较高,但血清胆固醇仍降低,胆固醇-卵磷脂指数降低,血清游离脂肪酸显著升高,这表明脂肪库中的脂肪分解增加。(所提及的饮食不均衡且不符合生理要求。在肥胖治疗中必须谨慎使用。只有在对每例无伴随疾病、不同意部分禁食且无法纳入强化运动方案的肥胖患者进行严格评估后,才可能应用该饮食方案。

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