Mosesso V N, Lukitsch K, Menegazzi J, Mosesso J
Department of Medicine, University of Pittsburgh School of Medicine, Pa 15213.
Prehosp Disaster Med. 1994 Jan-Mar;9(1):24-8. doi: 10.1017/s1049023x00040796.
Use of an oxygen-powered demand-valve to ventilate through an endotracheal tube is considered inappropriate due to concern regarding excessive airway pressures.
It was hypothesized that ventilation through an endotracheal tube using bag-valve (BV) device and the recently modified demand-valve (DV) would produce similar tidal volumes (Vt), minute ventilation (MV), and peak airway pressures (PAP).
This is a prospective, randomized in vitro experimental model. Subjects were blinded to volume and pressure gauges. Thirty-nine EMTs (mean age 27 years with mean experience five years) volunteered to ventilate a mechanical test lung through an endotracheal tube for 10 minutes. Each subject was randomized to BV or DV and to either normal (0.1 L/cm H 2O) or poor (0.04 L/cm H 2O) lung compliance. This DV delivers set flow of 40 L/min at maximum 50+/-5 cm H 2O. Subjects were instructed to use their "usual" technique for an average size adult in respiratory arrest with normal heart rate and blood pressure. The Vt and PAP were recorded for each breath; the MV and maximum PAP (PAP-max) for each minute was noted. Data were analyzed using repeated measures ANOVA and Tukey multiple comparisons with alpha set at 0.05.
Overall average tidal volumes and minute ventilations were acceptable with both ventilatory devices at both normal and poor compliance for the first, fifth, and 10th minute of continuous ventilation.(ABSTRACT TRUNCATED AT 250 WORDS)
由于担心气道压力过高,使用氧气驱动的需求阀通过气管内导管进行通气被认为是不合适的。
假设使用袋阀(BV)装置和最近改进的需求阀(DV)通过气管内导管进行通气会产生相似的潮气量(Vt)、分钟通气量(MV)和气道峰值压力(PAP)。
这是一个前瞻性、随机体外实验模型。受试者对容量和压力计不知情。39名急救医疗技术员(平均年龄27岁,平均经验5年)自愿通过气管内导管对机械测试肺进行10分钟的通气。每个受试者被随机分为BV组或DV组,并分为正常(0.1L/cm H₂O)或较差(0.04L/cm H₂O)肺顺应性。这种DV在最大50±5cm H₂O时提供40L/min的设定流量。指导受试者对呼吸骤停、心率和血压正常的平均体型成年人使用他们“常用”的技术。记录每次呼吸的Vt和PAP;记录每分钟的MV和最大PAP(PAP-max)。使用重复测量方差分析和Tukey多重比较对数据进行分析,α设定为0.05。
在正常和较差顺应性情况下,两种通气装置在持续通气的第一分钟、第五分钟和第十分钟的总体平均潮气量和分钟通气量均可接受。(摘要截断于250字)