Tomita N, Tamai S, Okajima E, Hirao Y, Ikeuchi K, Ikada Y
Department of Orthopedic Surgery, Nara Medical University, Kashihara, Japan.
J Appl Biomater. 1994 Summer;5(2):175-81. doi: 10.1002/jab.770050211.
To improve the frictional characteristics of a biomaterial, the mechanical performance of a lubricated surface was studied. In vitro friction tests showed that the coefficient of dynamic friction of the lubricated surface was about 0.01 against rabbit bladder and the coefficient of static friction increased with the preload period. The efficacy of a lubricated cystoscope was evaluated by an in vivo test simulating cystoscope operation. The maximal and the total resistance force on the cystoscope model were found to decrease with the surface lubrication. Histological study revealed that urethral damage caused by rubbing with the cystoscope model was reduced by this lubrication technique. Presumably, prolonged retention of water on the lubricated surface region prevented tissue adhesion to the foreign material.
为改善生物材料的摩擦特性,对润滑表面的力学性能进行了研究。体外摩擦试验表明,润滑表面与兔膀胱之间的动摩擦系数约为0.01,静摩擦系数随预加载时间增加。通过模拟膀胱镜操作的体内试验评估了润滑膀胱镜的效果。发现膀胱镜模型上的最大阻力和总阻力随表面润滑而降低。组织学研究表明,这种润滑技术减少了膀胱镜模型摩擦引起的尿道损伤。据推测,润滑表面区域水分的长时间保留可防止组织与异物粘连。