Kazmierska Katarzyna, Szwast Maciej, Ciach Tomasz
Faculty of Chemical and Process Engineering, Warsaw University of Technology, ul. Warynskiego 1, Warszawa, 00-645, Poland.
J Mater Sci Mater Med. 2008 Jun;19(6):2301-6. doi: 10.1007/s10856-007-3339-4. Epub 2007 Dec 12.
Device for in-vitro measurement of static and kinetic friction coefficient of catheter surface was developed. Tribometer was designed and constructed to work with exchangeable counter-faces (polymers, tissue) and various types of tubes, in wet conditions in order to mimic in-vivo process. Thus seven commercially available urethral catheters, made from vinyl polymers, natural latex with silicone coating, all-silicone or hydrogel coated, and one made from polyvinylchloride with polyurethane/polyvinylpyrrolidone hydrogel coating obtained in our laboratory, were tested against three various counter faces: polymethacrylate (organic glass), inner part of porcine aorta and porcine bladder mucosa. Additionally, the hydrophility/hydrophobity of tested catheters was stated via water wetting contact angle measurement. Super-hydrophilic biomaterials revealed low friction on tissue and hydrophobic counter-face; slightly hydrophobic showed higher friction in both cases, while more hydrophobic manifested low friction on tissue but high on hydrophobic polymer. The smoothest friction characteristic was achieved in all cases on tissue counter-faces. The measured values of the static coefficient of friction of catheters on bladder mucosa counter-face were as follows: the highest (0.15) for vinyl and siliconised latex catheters and 3 folds lower (0.05) for all-silicone ones. Hydrogel coated catheters exhibited the lowest static and kinetic friction factors.
开发了一种用于体外测量导管表面静摩擦系数和动摩擦系数的装置。设计并制造了摩擦计,使其能够在潮湿条件下与可更换的配对表面(聚合物、组织)以及各种类型的管子配合使用,以模拟体内过程。因此,对七种市售尿道导管进行了测试,这些导管由乙烯基聚合物、带硅酮涂层的天然乳胶、全硅酮或水凝胶涂层制成,还有一种是在我们实验室获得的由聚氯乙烯与聚氨酯/聚乙烯吡咯烷酮水凝胶涂层制成的导管,测试它们与三种不同的配对表面:聚甲基丙烯酸甲酯(有机玻璃)、猪主动脉内部和猪膀胱黏膜。此外,通过测量水的润湿接触角来确定被测导管的亲水性/疏水性。超亲水生物材料在组织和疏水配对表面上显示出低摩擦力;轻度疏水的在两种情况下都显示出较高的摩擦力,而疏水性更强的在组织上显示出低摩擦力,但在疏水聚合物上显示出高摩擦力。在所有情况下,在组织配对表面上获得了最平滑的摩擦特性。导管在膀胱黏膜配对表面上的静摩擦系数测量值如下:乙烯基和硅化乳胶导管最高(0.15),全硅酮导管则低3倍(0.05)。水凝胶涂层导管表现出最低的静摩擦系数和动摩擦系数。