Georgi G R, Weber R, Schmidt U J, Reinhardt C, Kalbe I
Z Alternsforsch. 1976;31(4):389-407.
In the present three parts of the survey ageing-changes in collagen physical and chemical qualities are discussed at first. Further a summary on questions of the biosynthesis of collagen, changes of the metabolism in the ageing organism and changes of the ripening collagen in the living organism is given. Following in vitro-ageing-changes of collagen and causes of the changes of the ageing organism are described. A summarizing appreciation of the ageing-changes in the collagen finishes the survey.
在本调查的三个部分中,首先讨论了胶原蛋白物理和化学性质的老化变化。此外,还总结了胶原蛋白生物合成问题、衰老生物体中新陈代谢的变化以及活生物体中成熟胶原蛋白的变化。接着描述了胶原蛋白的体外老化变化以及衰老生物体变化的原因。对胶原蛋白老化变化的总结性评价完成了本调查。