Moran J, Addy M, Wade W, Newcombe R
Department of Periodontology, University of Wales College of Medicine, Cardiff, UK.
Clin Mater. 1990;6(2):123-35. doi: 10.1016/0267-6605(90)90003-e.
Evidence to date has demonstrated the potential value of acrylic strips to deliver antimicrobial compounds into periodontal pockets. The present study was designed to evaluate further the therapeutic effect of antimicrobial acrylic strips in the management of chronic periodontitis. A total of 101 pockets in 69 patients were randomly treated with (1) chlorhexidine strips, (2) metronidazole strips, (3) tetracycline strips, (4) root planing, and (5) combined root planing and metronidazole strips. Immediately before and after treatment clinical measurements of disease were recorded over a three-month period. For all treatment groups significant improvements in clinical parameters were seen compared to control untreated sites but the most effective treatment was combined root planing and metronidazole and the least effective chlorhexidine. Although not significant, combined root planing and metronidazole also appeared to produce some adjunctive effects on clinical parameters compared to root planing alone. Antimicrobial acrylic strips appear useful treatments for chronic periodontitis, but should be used primarily as an adjunct to conventional root planing.
迄今为止的证据已证明丙烯酸条带将抗菌化合物输送到牙周袋中的潜在价值。本研究旨在进一步评估抗菌丙烯酸条带在慢性牙周炎治疗中的疗效。69例患者共101个牙周袋被随机分为五组接受治疗：（1）洗必泰条带；（2）甲硝唑条带；（3）四环素条带；（4）根面平整；（5）根面平整联合甲硝唑条带。在治疗前及治疗后三个月期间记录疾病的临床测量数据。与未治疗的对照部位相比，所有治疗组的临床参数均有显著改善，但最有效的治疗方法是根面平整联合甲硝唑，最无效的是洗必泰。虽然差异不显著，但与单纯根面平整相比，根面平整联合甲硝唑似乎也对临床参数产生了一些辅助作用。抗菌丙烯酸条带似乎是慢性牙周炎的有效治疗方法，但应主要用作传统根面平整的辅助手段。
