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[疑似先天性弓形虫病病例中特异性IgM抗体的检测:结果解读(作者译)]

[Demonstration of specific IgM antibody in cases of suspect congenital toxoplasmosis: interpretation of results (author's transl)].

作者信息

Werner H, Schöning C, Neuhaus B, Maute I

出版信息

Z Geburtshilfe Perinatol. 1976 Dec;180(6):438-44.

PMID:1014782
Abstract

From the aspect of laboratory Toxoplasmosis examination, a series of clinically and parasitologically confirmed cases of congenital Toxoplasmosis (CT) were selected. Serological findings (CFT, DT, IgM-IFAT) in infants and mothers were critically examined. The IgM titers in CT as a rule lay between 1:16 and 1:64, the highest recorded being 1:256. The serum IgM globulin levels showed no dependence on the high CFT titers. T recognize unspecific reactions amongst infants with positive IgM values, the serological testing of mothers was indispensable. It is also absolutely necessary with infants to repeatedly test serologically at intervals to clearly bring out the results of all the three serological reactions. The technical problems encountered for a definative diagnosis of CT and the clinical picture in the present critical examination are discussed.

摘要

从实验室弓形虫病检查方面,选取了一系列临床和寄生虫学确诊的先天性弓形虫病(CT)病例。对婴儿和母亲的血清学检查结果(补体结合试验、变形杆菌凝集试验、IgM间接荧光抗体试验)进行了严格检查。CT患者的IgM滴度通常在1:16至1:64之间,记录到的最高值为1:256。血清IgM球蛋白水平与高补体结合试验滴度无关。为识别IgM值呈阳性的婴儿中的非特异性反应,母亲的血清学检测必不可少。对婴儿进行间隔性血清学反复检测也绝对必要,以便明确所有三种血清学反应的结果。讨论了在本次严格检查中进行CT确诊时遇到的技术问题及临床表现。

相似文献

1
[Demonstration of specific IgM antibody in cases of suspect congenital toxoplasmosis: interpretation of results (author's transl)].[疑似先天性弓形虫病病例中特异性IgM抗体的检测:结果解读(作者译)]
Z Geburtshilfe Perinatol. 1976 Dec;180(6):438-44.
2
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Wiad Parazytol. 1997;43(1):39-51.
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Reliability of IgM-IFA and IgM-IHA tests on pure IgM fractions obtained by a simple gel filtration method in acquired and congenital toxoplasmosis.通过简单凝胶过滤法获得的纯IgM组分上进行IgM免疫荧光抗体试验(IgM-IFA)和IgM间接血凝试验(IgM-IHA)在获得性和先天性弓形虫病中的可靠性。
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Congenital toxoplasmosis: late pregnancy infections detected by neonatal screening and maternal serological testing at delivery.先天性弓形虫病:通过新生儿筛查和分娩时的母体血清学检测发现的晚期妊娠感染。
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