Sjöström L, Jonsson H, Karlström G, Olerud C, Olerud S
Department of Orthopaedic Surgery, University Hospital, Uppsala, Sweden.
Contemp Orthop. 1993 Mar;26(3):247-55.
Metastatic tumors often spread to the vertebral column. When the mechanical strength of a vertebra is decreased as a result of tumor-induced bone destruction, a pathologic fracture may occur. Such a fracture is often associated with severe pain. If it occurs in the thoracic or upper lumbar region, there is a major risk of paraplegia if the fractured vertebral body is displaced into the spinal canal. Metastases in the vertebral column also can cause neurologic symptoms due to direct infiltration of the tumor into the spinal canal. Due to recent advances in spinal surgery, effective help often can be provided to these patients. The extent and type of surgical intervention, however, must be carefully considered in each individual case.
转移性肿瘤常扩散至脊柱。当椎体因肿瘤导致的骨质破坏而机械强度下降时，可能会发生病理性骨折。这种骨折常伴有剧痛。如果发生在胸段或上腰段，若骨折椎体移位至椎管内，则有截瘫的重大风险。脊柱转移瘤也可因肿瘤直接浸润椎管而导致神经症状。由于脊柱外科的最新进展，通常可为这些患者提供有效的帮助。然而，在每个病例中，都必须仔细考虑手术干预的范围和类型。
