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经皮冠状动脉腔内血管成形术(PTCA)的最新进展:其局限性有哪些?新设备能否克服这些局限性?探讨斑块旋切术、动脉内支架和激光导管。

Update on PTCA: what are its limitations? Can they be overcome by new devices? A look at atherectomy, intra-arterial stents, and laser catheters.

作者信息

Feldman T, Moscucci M

机构信息

University of Chicago Pritzker School of Medicine.

出版信息

J Crit Illn. 1993 Apr;8(4):461-78.

Abstract

Complications limiting the use of percutaneous transluminal coronary angioplasty (PTCA) include abrupt vessel closure and restenosis. Certain coronary lesions, such as chronic total occlusions and diffuse or long stenoses, pose serious technical difficulties. New devices may overcome some of these limitations. For example, atherectomy may prove useful for thrombotic vessels or diffusely diseased vein grafts, and it may lower restenosis rates in larger vessels. Stents are currently used as a bailout measure when acute dissection occurs. Although lasers produce smoother margins than does conventional PTCA and effectively ablate atherosclerotic plaque material, the restenosis rate associated with use of these devices may be similar to that of conventional PTCA.

摘要

限制经皮腔内冠状动脉成形术(PTCA)应用的并发症包括血管突然闭塞和再狭窄。某些冠状动脉病变,如慢性完全闭塞以及弥漫性或长段狭窄,会带来严重的技术难题。新型器械或许能克服其中一些限制。例如,旋切术可能对血栓形成的血管或弥漫性病变的静脉移植物有用,并且可能降低较大血管的再狭窄率。当发生急性夹层时,支架目前被用作一种补救措施。尽管激光产生的边缘比传统PTCA更平滑,并且能有效消融动脉粥样硬化斑块物质,但使用这些器械相关的再狭窄率可能与传统PTCA相似。

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