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定向冠状动脉斑块旋切术治疗轮廓异常的冠状动脉病变。

Directional coronary atherectomy for the treatment of coronary lesions with abnormal contour.

作者信息

Hinohara T, Rowe M, Robertson G, Selmon M, Braden L, Simpson J B

机构信息

Department of Cardiology, Sequoia Hospital, Redwood City, California.

出版信息

J Invasive Cardiol. 1990 Mar-Apr;2(2):57-63.

Abstract

Directional coronary atherectomy is a newly developed percutaneous transluminal procedure which excises and removes obstructive tissue from coronary arteries or saphenous vein grafts. This procedure was performed on 47 lesions with abnormal contour; 24 ulcerative lesions, 10 lesions with dissection, 7 flap-like lesions and 6 lesions with aneurysm dilatation. Overall success rate was 89%; 96% in ulcerative lesions, 70% in lesions with dissection, 86% in flap-like lesions and 100% in lesions with aneurysmal dilatation. Complications with this procedure were as follows: Vessel occlusion in 2 patients (4.5%), perforation in 1 patient (2.3%), and guiding catheter induced dissection in 1 patient (2.3%). Coronary artery bypass surgery was required in 4 patients (9.4%) for these complications. Of these, 3 patients had lesions with dissections prior to the atherectomy procedure. The success rate for lesions with abnormal contour was similar to those of 270 lesions with normal contour. In conclusion, directional coronary atherectomy is a safe and effective procedure for lesions with abnormal contour, however, outcome of a lesion with dissection is suboptimal and it needs to be approached cautiously.

摘要

定向冠状动脉斑块旋切术是一种新开发的经皮腔内手术,可从冠状动脉或大隐静脉移植物中切除阻塞性组织。该手术针对47个轮廓异常的病变进行;24个溃疡性病变、10个有夹层的病变、7个瓣状病变和6个有动脉瘤扩张的病变。总体成功率为89%;溃疡性病变为96%,有夹层的病变为70%,瓣状病变为86%,有动脉瘤扩张的病变为100%。该手术的并发症如下:2例患者发生血管闭塞(4.5%),1例患者发生穿孔(2.3%),1例患者发生导引导管引起的夹层(2.3%)。因这些并发症,4例患者(9.4%)需要进行冠状动脉搭桥手术。其中,3例患者在斑块旋切术前有夹层病变。轮廓异常病变的成功率与270个轮廓正常病变的成功率相似。总之,定向冠状动脉斑块旋切术对于轮廓异常的病变是一种安全有效的手术,然而,有夹层的病变效果欠佳,需要谨慎处理。

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