Revina S K
Zh Vyssh Nerv Deiat Im I P Pavlova. 1976 Nov-Dec;26(6):1251-7.
Movements elicited by electrical stimulation (ES) of the brain's dorsal surface (train duration 20 msec, frequency 200 c/s) were studied in unanaesthetized slightly fixed rabbits. The stimuli were led through 80 mu in diameter electrodes implanted in the cortex. The responses were estimated visually or electromyographycally. The local responses of the forelimb (FL) were elicited by ES of an area with coordinates A 1-2, L 1-4; local movements of the hind limb (HL)--P 2,5-3,5 L 1-4. Between these areas there is a region whose stimulation caused the movements of the fore- and hind limb simultaneously ("overlapping area"). The thresholds and latencies of the forelimb responses were minimal when the stimuli were applied to the "local responses area". However, the tresholds and latencies of hindlimb responses were higher when stimulation was applied in the "local responses area" as compared with the "overlapping area". Light barbiturate anaesthesia (20 to 25 mg/kg) raised the thresholds of hindlimb movements 13 to 18 times when the stimuli were applied to the "local responses area", and 7 to 8 times, when they were applied to the "overlapping area". The problem of determination of the rabbit "motor centre" is discussed.
在未麻醉的轻度固定兔中,研究了通过电刺激(ES)脑背表面(串刺激持续时间20毫秒,频率200次/秒)引发的运动。刺激通过植入皮层的直径80微米的电极传导。通过视觉或肌电图评估反应。前肢(FL)的局部反应由坐标为A 1 - 2、L 1 - 4区域的电刺激引发;后肢(HL)的局部运动由坐标为P 2.5 - 3.5、L 1 - 4区域的电刺激引发。在这些区域之间有一个区域,刺激该区域会同时引起前肢和后肢的运动(“重叠区域”)。当刺激施加于“局部反应区域”时,前肢反应的阈值和潜伏期最小。然而,与“重叠区域”相比,当在“局部反应区域”施加刺激时,后肢反应的阈值和潜伏期更高。当刺激施加于“局部反应区域”时,轻度巴比妥类麻醉(20至25毫克/千克)使后肢运动的阈值提高13至18倍,当刺激施加于“重叠区域”时,阈值提高7至8倍。讨论了确定兔“运动中枢”的问题。