Hellener G, Cohn D, Marom G
Casali Institute of Applied Chemistry, Graduate School of Applied Science, Hebrew University of Jerusalem, Israel.
Clin Mater. 1994;16(4):195-200. doi: 10.1016/0267-6605(94)90117-1.
The model according to the Law of Laplace, describing the mechanical behaviour of blood vessels and vascular grafts, was applied to filament wound arterial prostheses, which have been manufactured with different winding angles. By varying the winding angle, the anisotropic behaviour of the grafts could be changed and fitted to the anisotropic properties of natural blood vessels. Thus, the Laplace model had to be modified, and answers now to the requirement of responding to the anisotropic behaviour in hoop versus axial direction of the grafts. The experimental data of hoop and axial compliances obtained by biaxial inflation tests could be then correlated to the material properties of the vascular grafts measured by uniaxial tensile loading. It is shown that with the modified Laplace model the changes in the anisotropic behaviour due to different winding angles can be described and predicted. The calculated compliance values derived from the uniaxial tensile tests fitted the experimental data obtained by the biaxial inflation tests, although the calculated hoop compliance values tended to be higher than the experimental data.
根据描述血管和血管移植物力学行为的拉普拉斯定律建立的模型，被应用于具有不同缠绕角度的纤维缠绕动脉假体。通过改变缠绕角度，可以改变移植物的各向异性行为，并使其与天然血管的各向异性特性相匹配。因此，必须对拉普拉斯模型进行修改，使其能够满足反映移植物环向与轴向各向异性行为的要求。通过双轴膨胀试验获得的环向和轴向顺应性的实验数据，随后可以与通过单轴拉伸加载测量的血管移植物的材料特性相关联。结果表明，利用改进后的拉普拉斯模型，可以描述和预测由于不同缠绕角度导致的各向异性行为的变化。虽然计算得到的环向顺应性值往往高于实验数据，但从单轴拉伸试验得出的计算顺应性值与双轴膨胀试验获得的实验数据相符。
