Bianchi-Marzoli S, Brancato R
Department of Ophthalmology and Visual Sciences, Scientific Institute San Raffaele Hospital, Milan, Italy.
Curr Opin Ophthalmol. 1994 Dec;5(6):11-7.
Optic nerve gliomas and meningiomas, which remain puzzling to clinicians, are reviewed with special attention to natural history, magnetic resonance findings, and appropriate management. New histopathological insights established the true neoplastic nature of optic nerve gliomas considered by most clinicians to be benign hamartomas. Unusual presenting manifestations and therapeutic alternatives of optic glioma have been also considered. Since the association of optic nerve gliomas and meningiomas with neurofibromatosis has long been recognized, special attention has been drawn to clinical, genetic, and ophthalmologic aspects of neurofibromatosis. New and unusual presenting manifestations, diagnostic and treatment opportunities concerning optic nerve involvement in metastatic disease, and lymphomatous proliferation are also described.
视神经胶质瘤和脑膜瘤一直令临床医生感到困惑，本文对此进行综述，特别关注其自然病史、磁共振成像结果及适当的治疗方法。新的组织病理学见解证实了大多数临床医生认为是良性错构瘤的视神经胶质瘤的真正肿瘤性质。文中还探讨了视神经胶质瘤不寻常的临床表现及治疗选择。由于视神经胶质瘤和脑膜瘤与神经纤维瘤病的关联早已为人所知，因此本文特别关注神经纤维瘤病的临床、遗传学及眼科方面。文中还描述了转移性疾病和淋巴瘤增殖累及视神经时新的及不寻常的临床表现、诊断及治疗机会。
