Jänig G R, Winkler W, Ruckpaul K, Rein H
Acta Biol Med Ger. 1976;35(7):K41-50.
The heme related circular dichroic bands of solubilized cytochrome P-450 from rabbit liver and some of its complexes with type I- and type II-substrayes and heme iron ligands were measured in the Soret region. All P-450 dersorption. The positions of the dichroic bands together with their ellipticities vary with ligand substitution and the oxidative state of the iron. The results are compared with CD-date of other hemoproteins and discussed with respect to stereochemical properties of the heme pocket.
在索雷特区域测量了来自兔肝的可溶性细胞色素P-450及其与I型和II型底物以及血红素铁配体的一些复合物的血红素相关圆二色性带。所有P-450解吸。二色性带的位置及其椭圆率随配体取代和铁的氧化态而变化。将结果与其他血红素蛋白的圆二色性数据进行比较，并就血红素口袋的立体化学性质进行了讨论。
