Schenk V W, Geene M J, Klein H W, Kredeit P, Stefanko S
Anat Embryol (Berl). 1976 Dec 22;150(1):53-62. doi: 10.1007/BF00346286.
The following malformations were observed in a human embryo of 28 mm crown-rump length obtained at operation for tubal rupture in a case of extrauterine pregnancy: 1. Secondary anophthalmia with dysplasia and in part aplasia of the diencephalon. Rudiments of both eyes and eyestalklike proliferations within the diencephalon. No lenses and on the left side only a palpebral fissure. Hypoplasia of the right telencephalic hemisphere and of the right side of diencephalon, mesencephalon and proximal parts of the medulla oblongata. Pseudotumorous proliferations in the diencephalon, in the alar plate of the medulla oblongata (protruding into the fourth ventricle) and in the arachnoid. Hypoplasia of the right internal, middle, and external ear. Dysplasia and in part aplasia of facial osseous elements (cebocephalia). 2. Proximal esophageal atresia with distal tracheoesophageal fistula. 3. A Fallot's tetralogy with right-sided aortic arch and regressive right-sided ductus arteriosus, tricuspid atresia, hypoplasia of the right ventricle with excessive hypertrophy of its wall, and hypoplasia of the pulmonary trunk. Single left superior vena cava and abnormal, semicircular course of the stems of both coronary arteries.
在一例宫外孕输卵管破裂手术中获取的一个冠臀长28毫米的人类胚胎上观察到以下畸形：1. 继发性无眼畸形，伴有间脑发育异常及部分发育不全。双眼原基及间脑内眼柄样增生。无晶状体，左侧仅有睑裂。右大脑半球、间脑右侧、中脑及延髓近端发育不全。间脑、延髓翼板（突入第四脑室）及蛛网膜有假肿瘤样增生。右内耳、中耳及外耳发育不全。面部骨质成分发育异常及部分发育不全（猴头畸形）。2. 食管近端闭锁伴远端气管食管瘘。3. 法洛四联症，伴有右侧主动脉弓及退化的右侧动脉导管、三尖瓣闭锁、右心室发育不全伴其壁过度肥厚，以及肺动脉干发育不全。单一左位上腔静脉，双侧冠状动脉主干走行异常呈半圆形。
