Bourret J A, Demers R F, Wordell D, Irani M, Baker J, Evangelista C
Hospital of the University of Pennsylvania, Philadelphia 19104, USA.
Pharm Pract Manag Q. 1996 Apr;16(1):1-17.
Fatal chemotherapy overdoses at prestigious institutions have prompted extensive reviews of policies and procedures in medical centers throughout the country. Improving medication use systems for chemotherapy requires a comprehensive multidisciplinary approach. A process to develop a medical center policy on chemotherapy based on the medication use model adopted by the Joint Commission on Accreditation of Healthcare Organizations will be discussed. This will include the prescribing, preparing, dispensing, administering, and monitoring process as well as quality improvement systems. Pharmacy information systems enhancements that safeguard patients are also discussed including maximum dose checks and specific dosing algorithms for bone marrow transplant patients.
著名机构发生的致命化疗药物过量事件促使全国各地的医疗中心对政策和程序进行了广泛审查。改进化疗药物使用系统需要采取全面的多学科方法。将讨论一个基于医疗保健机构认证联合委员会采用的药物使用模型制定医疗中心化疗政策的过程。这将包括开处方、配制、分发、给药和监测过程以及质量改进系统。还将讨论保障患者安全的药房信息系统改进措施，包括最大剂量检查和针对骨髓移植患者的特定给药算法。
