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对功能失调性子宫出血的绝经前女性进行队列分析。

A cohort analysis of pre-menopausal women with dysfunctional uterine bleeding.

作者信息

Horn S D, Prather S, Jones C A

机构信息

Institute for Clinical Outcomes Research (ICOR), Salt Lake City, UT 84109, USA.

出版信息

HMO Pract. 1996 Jun;10(2):59-64.

Abstract

OBJECTIVE

To examine the clinical and cost outcomes of patients with dysfunctional uterine bleeding (DUB) who are treated with hysterectomy or not.

DESIGN

A retrospective analysis of DUB patients over 30 months of treatment after initial diagnosis.

SETTING

Patients with DUB from an HMO with over 200,000 enrollees.

PARTICIPANTS

Study patients, all women with an initial diagnosis of DUB, were divided into two cohorts. Cohort 1 was women who had a hysterectomy (not for cancer); Cohort 2 was women who did not have a hysterectomy.

MAIN OUTCOME MEASURES

Visit counts and costs, prescription counts and costs, hospital costs, and procedure counts.

RESULTS

Hysterectomy patients in our dataset tend to have more prescriptions, higher prescription costs, more visits overall, higher visit costs, higher hospitalization costs, and higher total costs per member per month (PMPM) than non-hysterectomy patients. After surgery, the hysterectomy patients' costs and utilization PMPM are higher than those for the non-hysterectomy patients.

CONCLUSIONS

There is wide variation in the treatment of patients with DUB. Clinical practice improvement studies are needed to determine the appropriate treatments based on patient characteristics to achieve better outcomes for lower costs.

摘要

目的

研究接受子宫切除术和未接受子宫切除术的功能失调性子宫出血(DUB)患者的临床和成本结局。

设计

对初次诊断后接受30多个月治疗的DUB患者进行回顾性分析。

背景

来自一家拥有超过20万名参保人的健康维护组织(HMO)的DUB患者。

参与者

研究对象为所有初次诊断为DUB的女性患者,分为两个队列。队列1为接受子宫切除术(非因癌症)的女性;队列2为未接受子宫切除术的女性。

主要结局指标

就诊次数和费用、处方数量和费用、住院费用以及手术次数。

结果

我们数据集中接受子宫切除术的患者比未接受子宫切除术的患者往往有更多的处方、更高的处方费用、更多的总体就诊次数、更高的就诊费用、更高的住院费用以及更高的每月每位患者总成本(PMPM)。手术后,接受子宫切除术患者的成本和PMPM利用率高于未接受子宫切除术的患者。

结论

DUB患者的治疗方法存在很大差异。需要开展临床实践改进研究,以根据患者特征确定合适的治疗方法,从而以更低的成本实现更好的治疗效果。

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