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白内障和人工晶状体手术中的角膜。

The cornea in cataract and intraocular lens surgery.

作者信息

Hardten D R

出版信息

Curr Opin Ophthalmol. 1996 Feb;7(1):43-8. doi: 10.1097/00055735-199602000-00009.

Abstract

Advances in cataract surgery and intraocular lens implantation techniques continue to allow improved safety for the cornea. Complications can include mechanical or toxic injury of the endothelium, stripped Descemet's membrane, epithelial toxicity and disruption, infectious keratitis, or epithelial ingrowth. Most of the recent work has addressed endothelial cell survival after cataract extraction and lens implantation or in cases following secondary lens implantation. A great deal of controversy has been raised over the past year as to whether flexible open-loop anterior chamber lenses, iris-fixated posterior chamber lenses, or transsclerally sutured posterior chamber lenses are safest for the cornea. Even with additional data accumulating, it still is not clear which type of implant provides the best degree of safety in cases requiring secondary implantation. Certainly, both flexible open-loop anterior chamber lenses and bag-fixated posterior chamber lenses placed at the time of cataract surgery have a good record of safety for the cornea. Patients with keratoconjunctivitis sicca require extra lubrication to prevent epithelial toxicity at the time of surgery and also postoperatively. Methylcellulose-containing lubricants appear to be most protective of the corneal epithelium. Overall, cataract surgery and intraocular lens implantation is extremely safe with modern techniques.

摘要

白内障手术和人工晶状体植入技术的进步持续提高了角膜的安全性。并发症可能包括内皮细胞的机械性或毒性损伤、Descemet膜剥脱、上皮毒性与破坏、感染性角膜炎或上皮内生。近期的大部分研究聚焦于白内障摘除和晶状体植入后或二期晶状体植入后的内皮细胞存活情况。在过去一年里,关于可折叠开环前房型人工晶状体、虹膜固定后房型人工晶状体或经巩膜缝合后房型人工晶状体对角膜而言哪种最安全引发了大量争议。即便有更多数据不断积累,但在需要二期植入的情况下,哪种类型的植入物能提供最佳安全程度仍不明确。当然,白内障手术时植入的可折叠开环前房型人工晶状体和囊袋固定后房型人工晶状体对角膜而言都有良好的安全记录。患有干眼症的患者在手术时及术后都需要额外润滑以防止上皮毒性。含甲基纤维素的润滑剂似乎对角膜上皮最具保护作用。总体而言,采用现代技术进行白内障手术和人工晶状体植入极其安全。

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