Permiakov N K, Zimina L N
Arkh Patol. 1976;38(11):3-11.
Acute renal insufficiency (ARI) -- one of the most frequent manifestations of many exogenous intoxications. On the ground of a morphological investigation of 625 kidneys in poisoning with various poisons, the authors have come to the conclusion that the acute nephrotic syndrome is the basis of ARI in a "toxic" kidney". A morphological classification of the nephrotic syndrome is given: necrotic nephrosis hydropic nephrosis (glycolic nephrosis), cortical necrosis of the kidney, excretory nephrosis, acute lipid nephrosis. Morphological characteristics of the nephrotic syndrome forms referred to above are presented. Lesions of the kidney in exogenous intoxications are caused first of all by the direct toxic action of a poison. Toxic shock is an important factor in the development of ARI.
急性肾功能不全（ARI）——多种外源性中毒最常见的表现之一。通过对625例因各种毒物中毒的肾脏进行形态学研究，作者得出结论：急性肾病综合征是“中毒性”肾脏中ARI的基础。给出了肾病综合征的形态学分类：坏死性肾病、水肿性肾病（乙醇酸肾病）、肾皮质坏死、排泄性肾病、急性脂质肾病。介绍了上述肾病综合征各型的形态学特征。外源性中毒时肾脏的损害首先是由毒物的直接毒性作用引起的。中毒性休克是ARI发生发展的一个重要因素。
