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γ-氨基丁酸和甘氨酸在躯体-交感反射形成中的作用

[Participation of GABA and glycine in the formation of somato-sympathetic reflexes].

作者信息

Kovalev G V, Morozov I S, Petrov V I

出版信息

Biull Eksp Biol Med. 1976;82(11):1342-4.

PMID:1016716
Abstract

Experiments were conducted on cats with intact spinal cord, and after spinalization a study was made of the action of strychnine and picrotoxin (synaptic GABA and glycine antagonists) on the components of somatosynaptic reflexes caused by stimulation of the skin and muscular intercostal afferents. Induced potentials were recorded in the white ramus of the third thoracic segment. The action of strychnine and picrotoxin on the values of different reflex components was not identical; this pointed to a different localization of the inhibitory action of GABA and glycine in the central link of the somatosympathetic reflex arch.

摘要

对脊髓完整的猫进行了实验,并在脊髓横断后,研究了士的宁和印防己毒素(突触GABA和甘氨酸拮抗剂)对刺激皮肤和肋间肌传入神经引起的躯体突触反射成分的作用。在第三胸段的白交通支中记录诱发电位。士的宁和印防己毒素对不同反射成分的值的作用并不相同;这表明GABA和甘氨酸的抑制作用在躯体交感反射弧的中枢环节中具有不同的定位。

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