Valvas V S
Biull Eksp Biol Med. 1976;82(11):1367-9.
A study was made of pain stimulus (amputation of 1/3 of the tail) on the mitotic activity in the corneal epithelium of 21-day fetuses, 1-, 3-, 4-, 5-, 7-, 10-, 15-, 20- and 25-day rats. In 45 minutes after the infliction of trauma no significant change was seen in the cornea of the fetuses and of the one-day-old ratlings. A gradual establishment of the reactive inhibition of mitoses in response to pain occurred between the 3rd and the 10th day of postnatal development. This reaction became more intense after the 10th day, reaching the maximum by the 25th day. Reactive inhibition of the mitotic activity was connected with the inhibition of the entrance of cells into mitosis.
对21日龄胎儿、1日龄、3日龄、4日龄、5日龄、7日龄、10日龄、15日龄、20日龄和25日龄大鼠的角膜上皮细胞有丝分裂活性进行了疼痛刺激（截断1/3尾巴）的研究。在施加创伤45分钟后，胎儿和1日龄幼鼠的角膜未见明显变化。出生后第3天至第10天之间，因疼痛而对有丝分裂的反应性抑制逐渐形成。这种反应在第10天后变得更强烈，到第25天达到最大值。有丝分裂活性的反应性抑制与细胞进入有丝分裂的抑制有关。
