Tusques J, George Y, Roch M
Bull Assoc Anat (Nancy). 1976 Mar;60(168):231-41.
The numerous synapses in the normal human brain cortex display various aspects. The authors have also observed some electronic type synapses which are more numerous around the pericaryons. The cortical synapses are classed according to their synaptic vesicle richness : synapses with very few vesicles, synapses very rich in vesicles and synapses with a middling vesicular density. With the help of observations on these aspects and on variations of the synaptic cleft and that of the postsynaptic density, the authors advance an hypothesis on synaptic plasticity, the synaptic structures going from a simple intercellular contact (probably non functional) to a completly formed synapse and vice versa.
正常人类大脑皮层中的众多突触呈现出不同的方面。作者还观察到一些电子型突触，它们在神经元胞体周围更为密集。皮质突触根据其突触小泡的丰富程度进行分类：小泡极少的突触、小泡非常丰富的突触以及小泡密度中等的突触。借助对这些方面以及突触间隙和突触后密度变化的观察，作者提出了一个关于突触可塑性的假说，即突触结构从简单的细胞间接触（可能无功能）发展为完全形成的突触，反之亦然。
