Siegel R J, Bessen M, Chae J, Potkin B, Coll G, Fishbein M C, Helfant R H
Division of Cardiology, Cedars-Sinai Medical Center, Los Angeles, CA 90048.
Echocardiography. 1990 May;7(3):181-92. doi: 10.1111/j.1540-8175.1990.tb00363.x.
In this paper we review the current status of intravascular ultrasound. Data from qualitative and quantitative studies is presented. Our experimental findings and those of other investigators are reviewed. Intravascular ultrasound has been shown to delineate normal and abnormal arterial morphology as well as to identify and differentiate fibrous, lipid-rich, calcified plaques and complicated plaques. Quantitative studies show strong correlations between ultrasound and histology for lumen area, wall thickness, and plaque area. In vivo studies from our experimental work and clinical laboratory as well as the work of other researchers is presented. This data supports the potential of ultrasound imaging for guidance of intravascular intervention. The potential advantages and limitations of this new technology are discussed. This methodology shows promise for the assessment of the extent and severity of atherosclerosis, monitoring its progression and regression and guiding intravascular plaque ablation technologies.
在本文中，我们回顾了血管内超声的现状。呈现了定性和定量研究的数据。我们的实验结果以及其他研究者的结果都进行了回顾。血管内超声已被证明能够描绘正常和异常的动脉形态，以及识别和区分纤维斑块、富含脂质的斑块、钙化斑块和复杂斑块。定量研究表明，超声与组织学在管腔面积、管壁厚度和斑块面积方面具有很强的相关性。展示了来自我们实验工作和临床实验室的体内研究以及其他研究者的工作。这些数据支持了超声成像在血管内介入指导方面的潜力。讨论了这项新技术的潜在优势和局限性。这种方法在评估动脉粥样硬化的范围和严重程度、监测其进展和消退以及指导血管内斑块消融技术方面显示出前景。
