Claes L E, Dürselen L, Rübenacker S
Abteilung Unfallchirurgische Forschung und Biomechanik, Universität Ulm, Germany.
Clin Mater. 1994;15(1):15-22. doi: 10.1016/0267-6605(94)90004-3.
Six different ligament prostheses were implanted in 40 sheep to replace the anterior cruciate and medial collateral ligament of the right knee. After one year the explanted knee joints were tested for stability by measurement of the anterior drawer. Tensile tests on the ligament replacements were performed to determine the stiffness and rupture force of the replacement. Gross inspection of the knee joint showed abrasion and partial ruptures for all types of prostheses after one year. Depending on the type of prosthesis total rupture rates between 0 and 66% of all implants could be seen. The anterior drawer for the operated knee was 3-4 times higher than for the non-operated contralateral side. Neither the stiffness nor the rupture strength of the replacements reached the biomechanical properties of the normal ligaments.
将六种不同的韧带假体植入40只绵羊体内，以替换右膝的前交叉韧带和内侧副韧带。一年后，通过测量前抽屉试验来检测取出的膝关节的稳定性。对韧带替代物进行拉伸试验，以确定替代物的刚度和断裂力。膝关节大体检查显示，一年后所有类型的假体均出现磨损和部分断裂。根据假体类型的不同，所有植入物的总断裂率在0%至66%之间。手术侧膝关节的前抽屉试验结果比未手术的对侧膝关节高3至4倍。替代物的刚度和断裂强度均未达到正常韧带的生物力学性能。
