某些巯基化合物和二甲基亚砜对铜绿假单胞菌中某些胺类和蛋白质释放钾的影响。
Effect of certain sulphydryl compounds and dimethyl sulphoxide on potassium release by certain amines and proteins from Pseudomonas aeruginosa.
作者信息
Bernheim F
出版信息
Microbios. 1977;19(77-78):151-6.
PMID:101739
Abstract
Dithiothreitol, cysteine, and mercapto-ethanol inhibit K+ release from cells of Pseudomonas aeruginosa by amines and NH4Cl incubated at pH 8.5. The inhibitions are competitive for the monamines and NH4Cl but non-competitive for the diamines and spermidine. The percent inhibition is largest for tryptamine, least for spermidine and ethylene diamine. DMSO inhibits K+ release by monamines and certain proteins but not significantly by diamines and histamine. The inhibitions are competitive.
摘要
二硫苏糖醇、半胱氨酸和巯基乙醇可抑制铜绿假单胞菌细胞在pH 8.5条件下经胺类和氯化铵孵育后钾离子的释放。这些抑制作用对单胺类和氯化铵是竞争性的，但对二胺类和亚精胺是非竞争性的。抑制百分比对色胺最大，对亚精胺和乙二胺最小。二甲基亚砜可抑制单胺类和某些蛋白质介导的钾离子释放，但对二胺类和组胺的抑制作用不明显。这些抑制作用是竞争性的。
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