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巴氏试验重新筛查的效用和成本效益。

The utility and cost-effectiveness of Pap test rescreening.

作者信息

Raab S S

机构信息

Department of Pathology, Allegheny University of Health Sciences, Allegheny General Hospital, Pittsburgh, PA, USA.

出版信息

Clin Lab Manage Rev. 1998 Mar-Apr;12(2):91-6.

PMID:10178714
Abstract

Although most laboratories practice 10% manual rescreening of negative Pap tests, the cost-effectiveness of this and other rescreening strategies rarely has been evaluated. A decision model was created in which rescreening strategies were compared with nonrescreening strategies in terms of the number of false negative and positive diagnoses, cancers, life expectancy, and cost-effectiveness. The 10% rescreening with a repeat Pap test strategy yielded almost no gain in life expectancy in comparison to an equivalent strategy with no rescreening. A 100% rescreening strategy generally was more cost-effective than a no-rescreening strategy at costs of rescreening varying from $2 to $10 per patient. We conclude that if the rescreening cost is low, 100% rescreening strategies are more cost-effective than nonrescreening strategies.

摘要

尽管大多数实验室对阴性巴氏试验进行10%的人工复查,但这种及其他复查策略的成本效益很少得到评估。创建了一个决策模型,在该模型中,就假阴性和阳性诊断数量、癌症、预期寿命和成本效益而言,将复查策略与不复查策略进行了比较。与不进行复查的等效策略相比,采用重复巴氏试验策略进行10%的复查在预期寿命方面几乎没有增加。在每位患者2至10美元的复查成本下,100%的复查策略通常比不复查策略更具成本效益。我们得出结论,如果复查成本较低,100%的复查策略比不复查策略更具成本效益。

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