Connolly J
J Human Stress. 1976 Dec;2(4):3-17. doi: 10.1080/0097840X.1976.9936069.
One-hundred and-twenty-one men between the ages of 35 and 65 who had been admitted to a Coronary Care Unit were interviewed within a mean of 2.3 days of that admission, concerning their experience of certain specified predesignated life events in the previous three months before myocardial infarction. Ninety-one of them who were proven to have sustained a myocardial infarction were randomly matched individually with 91 men from an industrial payroll for sex, age and occupational level. Both groups matched, as groups, on marital status and household size. Significantly more patients (p less than .01) than comparison subjects reported these life events in the three weeks before infarction, whether this was experienced acutely or in an anginal setting. Most events were apparently independent of patients' or comparison subjects control; these were reported significantly more often by patients, both during the entire 12 weeks prior to illness (p less than .01) and during the three weeks immediately before infarction (p less than .02). Methodological difficulties are delineated which hinder credence as to the role of life events before illness.
121名年龄在35岁至65岁之间、入住冠心病监护病房的男性患者，在入院平均2.3天内接受了访谈，询问他们在心肌梗死前三个月内某些特定预先指定的生活事件的经历。其中91名被证实发生过心肌梗死的患者，按照性别、年龄和职业水平，与91名来自企业工资单上的男性进行了个体随机匹配。两组在婚姻状况和家庭规模上作为一个整体进行了匹配。无论是急性发作还是心绞痛发作，与对照组相比，更多的患者（p<0.01）报告在梗死前三周经历了这些生活事件。大多数事件显然不受患者或对照对象控制；在整个患病前12周（p<0.01）以及梗死前三周（p<0.02），患者报告这些事件的频率明显更高。文中阐述了一些方法学上的困难，这些困难阻碍了人们对疾病前生活事件作用的信任。
