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质量调整生命年与健康效用指数——何为正确,何为错误。争议综述。

QALYs versus HYEs--what's right and what's wrong. A review of the controversy.

作者信息

Ried W

机构信息

Department of Economics, University of Mannheim, Germany.

出版信息

J Health Econ. 1998 Oct;17(5):607-25. doi: 10.1016/s0167-6296(97)00037-4.

DOI:10.1016/s0167-6296(97)00037-4
PMID:10185514
Abstract

The paper uses an axiomatic approach to the description of individual preferences for health status sequences to resolve the major issues at state in the recent controversy over QALYs versus HYEs. While the HYE accounts for an individual's time preference for health, QALY scores based on the time trade-off method will generally differ from the number of HYEs. HYEs do not represent preferences for health under risk unless the utility function for reference flows of health is linear. Collapsing the two-step HYE assessment procedure into a single step entails a loss of information as regards the utility of a health status sequence. Although the procedure does represent preferences for health, it fails to supply a description in terms of HYEs in the case of risk. As a remedy, a modified HYE approach is proposed.

摘要

本文采用公理化方法来描述个体对健康状况序列的偏好,以解决最近关于质量调整生命年(QALYs)与健康年当量(HYEs)争议中的主要问题。虽然健康年当量考虑了个体对健康的时间偏好,但基于时间权衡法的质量调整生命年得分通常会与健康年当量的数量有所不同。除非健康参考流的效用函数是线性的,否则健康年当量并不代表风险下的健康偏好。将两步健康年当量评估程序合并为一步会导致在健康状况序列效用方面的信息损失。虽然该程序确实代表了对健康的偏好,但在存在风险的情况下,它未能提供基于健康年当量的描述。作为一种补救措施,提出了一种改进的健康年当量方法。

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