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[丹曲林钠(丹曲林)治疗神经源性肌肉痉挛]

[Sodium dantrolene (dantrium) in the treatment of neurogenic muscular spasm].

作者信息

Couto B, Figuereido H B, Araújo Leitão R E, Alvarenga H, Gomes Marleide M, Melo Reis C H

出版信息

Neurol Neurocir Psiquiatr. 1976;17(4):213-21.

PMID:1018726
Abstract

Forty patients, whose ages varied from 4 to 65 years, presenting skeletal muscle spascitiy as sequel of cerebral palsy, spinovertebral trauma and cerebral vascular diseases were treated with Dantrium (dantrolene sodium), a drug muscle relaxing. Laboratory data included: electromiography, chronaximetry, EEG and blood and urine tests. Clinical followup revealed subjective improvement in the patients and also objective decrease of spasticity in a satisfactory number. Patients who had improvement with this therapy also had no beneficial results with other drugs.

摘要

40名年龄在4岁至65岁之间、因脑瘫、脊柱椎骨创伤和脑血管疾病后遗症而出现骨骼肌痉挛的患者接受了丹曲林(硝苯呋海因钠)治疗,这是一种肌肉松弛药物。实验室数据包括:肌电图、时值测定、脑电图以及血液和尿液检查。临床随访显示患者主观症状有所改善,并且相当数量患者的痉挛客观上有所减轻。接受该疗法有改善的患者使用其他药物均未取得有益效果。

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