Kriz M, Gazdik M
Neurol Neurochir Pol. 1978 Jul-Aug;12(4):413-9.
The study presents the results of a long term investigation of 60 epileptic children with Rolandic (centrotemporal) spikes in EEG. The results could be summarized as follows: the Rolandic epilepsy is relatively frequent entity (13.4% of the total number of epileptic children). The age span was from 3--13 years, with a peak of age incidence between the 7th and 8th year of life. More than half of children had nocturnal fits only. From the clinical point of view 60% of children had generalized crises, and the remaining 40% had partial attacks corresponding to the functional organization of the Rolandic cortical area. The evolution of the Rolandic epilepsy in childhood is favourable. More than 50% didn't have more attacks after the introduction of antiepileptic therapy, and 3/4 of them could be classified as practically cured after an long-term follow-up (criterion: an attack-free period of at least 5 years. Finally, in more than 80% of cases after three years of follow-up the spikes have disappeared from the EEG tracings which were completely normal.
该研究展示了对60名脑电图显示有中央颞区（罗兰多区）棘波的癫痫儿童进行长期调查的结果。结果可总结如下：罗兰多区癫痫是一种相对常见的病症（占癫痫儿童总数的13.4%）。年龄跨度为3至13岁，发病年龄高峰在7至8岁之间。超过一半的儿童仅在夜间发作。从临床角度来看，60%的儿童有全身性发作，其余40%有与罗兰多皮质区功能组织相对应的部分性发作。儿童期罗兰多区癫痫的病情发展较为乐观。超过50%的儿童在开始抗癫痫治疗后不再发作，经过长期随访，其中四分之三可被归类为基本治愈（标准：至少5年无发作期）。最后，在超过80%的病例中，经过三年随访，脑电图上的棘波已消失，脑电图完全正常。
